Articles

Guides

The following pages provide illustrations of how to conduct simulations.

Simple Mendelian randomisation examples

Simple two-sample Mendelian randomisation examples

Simulating GWAS summary data

Theory and experiments

A set of notebooks that give some background to the functions in the package

Sample overlap in GWAS summary datasets

Simulating summary data for weak instruments

Background notes: Simulating GWAS summary data

LD matrices

Data generating process for genetic effects on complex traits with interactions

Simulating GWAS summary data with LD

Generating LD matrices

Comparing SuSIE results with summary level vs individual level simulations

Directly simulating summary datasets with sample overlap