Estimate proportion of variance of liability explained by SNP in general population

This uses equation 10 in Genetic Epidemiology 36 : 214–224 (2012)

lor_to_rsq(b, af, ncase, ncontrol, prevalence, model = "logit")

Arguments

b

Log odds ratio

af

allele frequency

ncase

Number of cases

ncontrol

number of controls

prevalence

prevalence

model

Is the effect size estiamted in "logit" (default) or "probit" model

Value

Rsq